當(dāng)前位置 ： Millipore >>> Millipore/ABN37 | Anti-Homer1 Antibody/ABN37/100 µg
Millipore/ABN37 | Anti-Homer1 Antibody/ABN37/100 µg
  • Millipore/ABN37 | Anti-Homer1 Antibody/ABN37/100 µg

Millipore/ABN37 | Anti-Homer1 Antibody/ABN37/100 µg

價(jià)格: ￥3948.00 市場價(jià): 6580.00
貨號(hào): ABN37
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請(qǐng)仔細(xì)核對(duì)信息。
下單后請(qǐng)及時(shí)聯(lián)系客服核對(duì)商品價(jià)格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費(fèi)服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價(jià)
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberABN37
      DescriptionAnti-Homer1Antibody
      AlternateNames
      • Homerproteinhomolog1
      • Homer-1
      • Homer1
      BackgroundInformationHomerproteinhomolog1(UniProtQ86YM7;alsoknownasHomer-1,Homer1)isencodedbytheHOMER1(alsoknownasSYN47)gene(GeneID9456)inhuman.Homer-1,-2,and-3constituteafamilyofpostsynapticscaffoldproteinsthatplayacentralroleincalciumsignaling.HomermembersshareaconservedN-terminalEna/VASPhomology1(EVH1)domain(a.a.1-110ofHomer-1)thatmediatesignalingcomplexesassemblybyinteractingwithPPXXFRproline-richconsensussequencesfoundinvariousotherscaffoldingandsignaltransductionmolecules,includingmetabotropicglutamatereceptors(mGluRs)and1,4,5-trisphosphatereceptors(IP3Rs).InadditiontomediategroupImGluRssignalingviatheirEVH1domain,Homer-1splicedvariantsVesl-1L,1b,and1d,butnotVesl-1MorVesl-1S,alsocontainaC-terminalcoiled-coil(a.a.181-352)regionthatmediateself-multimerization.Homer-1variantsareassociatedwiththeetiologyofmanyneurologicaldiseases,suchaschronicpain,mentalretardationsyndromes,Alzheimer"sdisease(AD),Parkinson"sdisease(PD),schizophrenia,drug-inducedaddiction,andtraumaticbraininjury(TBI).Homer1b/c-knockdownisreportedtoprotectagainstchemicallyinducedseizureinmiceasaresultofpreventingmGluR5-mediatedmTORpathwayactivation.
      ProductInformation
      FormatAffinityPurified
      Control
      • Mousebraintissuelysate.
      PresentationPurifiedrabbitpolyclonalantibodyinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide.
      StorageandShippingInformation
      StorageConditionsStablefor1yearat2-8°Cfromdateofreceipt.
      Applications
      ApplicationAnti-Homer1,Cat.No.ABN37,isahighlyspecificrabbitpolyclonalantibodythattargetsHomerproteinhomolog1andhasbeentestedinImmunohistochemistryandWesternBlotting.
      KeyApplications
      • WesternBlotting
      • Immunohistochemistry(Paraffin)
      ApplicationNotesImmunohsitochemistryAnalysis:A1:500dilutionfromarepresentativelotdetectedHomer1inhumanandmousecerebralcortextissuesections.

      ImmunohsitochemistryAnalysis:ArepresentativelotdetectedsignificantlyincreasedstratumrADIatumandstratumoriensHomer1immunoreactivityinfloatingbrainsectionsfrommicereceivedAP-12intraperitonealinjection(Jansone,B.,etal.(2015).PLoSOne.10(6):e0127686).
      BIOLOGicalInformation
      ImmunogenKLH-conjugatedlinearpeptidecorrespondingtoaninternalsequencewithintheN-terminalhalfofhumanHomer1isoform1bandneartheC-terminusofisoform1h.
      ConcentrationPleaserefertolotspecificdatasheet.
      HostRabbit
      SpecificityThisrabbitpolyclonalantibodytargetsaninternalsequencewithintheN-terminalhalfofhumanHomer1isoform1bandmouseisoformVesl-1L.ImmunogensequenceappearsneartheC-terminusofhumanisoform1handmouseisoforms1b,1d,Vesl-1M,andVesl-1S,butabsentinhumanisoform1e.Highlyhomologoussequence(~83%)isalsofoundintheN-terminalhalfofratisoform1c(Vesl-1L)andneartheC-terminusofratisoforms1a(Vesl)and1b.
      SpeciesReactivity
      • Human
      • Mouse
      SpeciesReactivityNoteHuman,Mouse.PredictedtoreactwithHorseandMonkeybasedon100%sequencehomology.Broadspeciesreactivityexpectedbasedonhighsequencehomology.
      AntibodyTypePolyclonalAntibody
      EntrezGeneNumber
      EntrezGeneSummaryThisgeneencodesamemberofthehomerfamilyofdendriticproteins.Membersofthisfamilyregulategroup1metabotrophicglutamatereceptorfunction.
      GeneSymbol
      • HOMER1
      • SYN47
      PurificationMethodAffinitypurfied.
      UniProtNumber
      MolecularWeight~47kDaobserved.40.28/19.86kDa(humanisoform1b/1h),40.22/42.08/41.41/22.78/20.91kDa(mouseisoform1b/1d/Vesl-1L/Vesl-1M/Vesl-1S)calculated.Uncharacterizedbandsmaybeobservedinsomelysate(s).
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度，由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價(jià)格”為理念，直接鏈接原廠家，從全國各地原制造商嚴(yán)格挑選188款科研精品，剔除品牌溢價(jià)，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗(yàn)，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團(tuán)隊(duì)負(fù)責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴(yán)格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進(jìn)行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費(fèi)金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達(dá)！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時(shí)免費(fèi)服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯(cuò)了怎么辦？
    A：同個(gè)訂單購買多個(gè)商品可能會(huì)分為一個(gè)以上包裹發(fā)出，可能不會(huì)同時(shí)送達(dá)，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時(shí)間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個(gè)月內(nèi)（以快遞公司顯示簽收時(shí)間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請(qǐng)?jiān)谑盏截?4小時(shí)內(nèi)申請(qǐng)退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn)，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因?yàn)樯偎跃劢?，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點(diǎn)擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號(hào)

獲取最新優(yōu)惠活動(dòng)通知