Immunogen | SyntheticpeptidefromratCRMP-2. |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | CollapsinResponseMediatorProtein2(CRMP-2).TheimmunogensequenceshareshomologywithCRMP-3andthereforemayshowcross-reactivity. |
SpeciesReactivity | |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol | - DPYSL2
- DHPRP2
- CRMP-2
- DRP-2
- N2A3
- CRMP2
- DRP2
|
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q16555#Involvedinneuronalgrowthconecollapse(Bysimilarity).Inducesaxonformation. SIZE:572aminoacids;62294Da SUBUNIT:InteractsthroughitsC-terminuswiththeC-terminusofCYFIP1/SRA1. SUBCELLULARLOCATION:Cytoplasm(Potential). TISSUESPECIFICITY:Ubiquitous. PTM:3F4,amonoclonalantibodywhichstronglystainsneurofibrillarytanglesinAlzheimerdiseasebrains,specificallylabelsDPYSL2whenphosphorylatedonSer-518,Ser-522andThr-509. SIMILARITY:SwissProt:Q16555##Belongstothedehydropyrimidinasefamily. |