Description:GoatpolyclonalantibodytoVimentin.VIMisamemberoftheintermediatefilamentfamily.TheCytoskeletonismadebytheseintermediatefilaments,alongwithactinMICROFILamentsandmicrotubules.VIMisresponsIBLeforintegrityofthecytoplasm,stABIlizationofthecytoskeletalinteractionsandmaintainingcellshape.ThisproteincontrolsthetransportofLDL-derivedcholesterolfromalysosometothesiteofesterificationandisalsoinvolvedintheimmuneresponse.Itfunctionsasanorganizerofanumberofcriticalproteinsinvolvedinmigration,attachmentandcellsignaling.Alternativenames:CTRCT30,Epididymisluminalprotein113,FLJ36605,HEL113,VIMantibody.
Form:Polyclonalantibodysuppliedasa100μl(2mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.
Immunogen:Recombinantpeptidederivedfromwithinresidues390aatotheC-terminusofhumanVIMproducedinE.coli.
Specificity:DetectsendogenouslevelsofVIMbyWesternblot.
Reactivity:Reactsagainsthuman,rat,mouse,canineandmonkeyproteins.
Storage:Storeat-20Cforlong-termstorage.Storeat2-8Cforuptoonemonth.
Specialinstructions:Avoidfreeze/thawcycles.