Immunogen | KLH-conjugatedlinearpeptidecorrespondingtomouseTbr1. |
Epitope | Internal |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Chicken |
Specificity | ThisantibodyrecognizesTbr1. |
SpeciesReactivity | - Human
- Mouse
- Rat
- Horse
- Pig
- Opossum
- Bovine
- Canine
|
SpeciesReactivityNote | Proventoreactwithhuman,mouse,andrat.Predictedtoreactwithhorse,pig,opossum,bovine,andcaninebasedon100%sequencehomology. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol | |
PurificationMethod | AffinityPurfied |
UniProtNumber | |
UniProtSummary | FUNCTION:Probabletranscriptionalregulatorinvolvedindevelopmentalprocesses.TBR1isrequiredfornormalbraindevelopment.
SUBCELLULARLOCATION:NucleusPotential.
TISSUESPECIFICTY:Expressedinspecificlaminainthedevelopingandadultbrain.
DEVELOPMENTALSTAGE:Firstdetectedaroundday10ofembryonicdevelopmentinthepreplate,atday12.5,inthecorticalplateandintermediatezone,andfromday16.5to18.5,inarostro-caudalgrADIentinthesubplate.Inthethalamus,expressionisfirstobservedatpostnatalstage,P7,andweakexpressioncontinuesinlaterpostnatalandadultstages.
SEQUENCESIMILARITIES:Contains1T-boxDNA-bindingdomain. |
MolecularWeight | ~68kDaisobserved;however,UniProtKB/Swiss-ProtentryQ64336(TBR1_MOUSE)listsamassof73.941kDa. |